💻 Synthetic Biology Foundation: Methods and Fidelity in the DNA Synthesis Market
The DNA Synthesis Market provides services and products for the artificial construction of nucleic acid sequences, primarily oligonucleotides (short DNA/RNA strands) and synthetic genes. This market is a critical enabler of the rapidly expanding fields of synthetic biology, gene editing, and functional genomics.DNA Synthesis Market.
The foundational method remains Phosphoramidite Chemistry, which is highly automated and scalable for synthesizing oligonucleotides used as $\text{PCR}$ primers, probes, and components for larger gene assembly. However, innovation is focused on improving the Fidelity (Accuracy) and Throughput of synthesis, as current chemical methods can introduce errors, which limits the length of usable synthetic $\text{DNA}$. Novel approaches, including Enzymatic DNA Synthesis (EDS), which uses DNA polymerases to assemble strands, promise to offer faster, higher-fidelity, and potentially more sustainable synthesis methods, driving the next generation of applications
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